%!TeX Encoding=GBK
\documentclass{twarticle}
% temp.map
%default SimSun
%细明 GBK2K-H SimSun
%中黑 GBK2K-H STZHONGS.TTF
%中楷 GBK2K-H STZHONGS.TTF
% simsun.ttc -a 859 -d -141
% STZHONGS.TTF -a 800 -d 200
\begin{document}
调整后：你好{\it 你好}

\PUXcfacedepth\PUXFmb=141
调整后：你好{\bf 你好}
\end{document}